gelatinase a การใช้

• This enzyme is similar to gelatinase A, but possesses a further domain.
• Matrix metalloproteinases ( MMP ), which catalyse extracellular matrix degradation, have N-terminal domains that resemble PGBD . Examples are gelatinase A ( MMP-2 ), which degrades type IV collagen, stromelysin-1 ( MMP-3 ), which plays a role in arthritis and tumour invasion, and gelatinase B ( MMP-9 ) secreted by neutrophils as part of the innate immune defence mechanism.